Regeneten Arthroscopic Surgery
Reinforce the Tendon with a Collagen Patch
For bursal-side partial rotator cuff tears, an arthroscopic surgery placing a collagen patch (Regeneten) over the torn surface. No general anesthesia — BPB (brachial plexus block) + sedation. 16% tendon thickness increase clinically proven (Arthroscopy 2024).
Regeneten — Bioabsorbable Collagen Matrix
Regeneten is a biocompatible collagen patch derived from porcine small intestinal submucosa (SIS). It is placed over the torn bursal surface of the rotator cuff to physically support the tendon while naturally promoting tissue regeneration through collagen scaffold integration.
Which tears is this best for?
Particularly effective for bursal-side (bursal surface) partial tears where the outer surface of the rotator cuff has thinned or partially torn. Unlike articular-side tears (treated with plication suture), bursal-side defects can be physically reinforced with a patch overlay.
Why Regeneten Works
Dual mechanism: physical support + biological regeneration
The patch provides immediate mechanical reinforcement to the weakened tendon, while the collagen scaffold integrates with the native tissue, stimulating cell ingrowth and new collagen synthesis.
Fully bioabsorbable — no permanent foreign material
Over approximately 6 months, the patch is naturally resorbed and replaced by the patient's own tissue. No metal anchors or permanent implants remain in the body.
FDA & CE approved material
Regeneten is a CE-marked and FDA-cleared medical device used globally for rotator cuff augmentation. Its safety and efficacy are well-established in clinical literature.
Published Research on Regeneten
Reference
Arthroscopy (2024): Regeneten bioinductive collagen implant group showed significant tendon thickness increase vs control(4.52mm vs 3.9mm, ~16% increase, P=.024). Patch fully absorbed by 6 months, replaced by native tissue.
Editorial Commentary: Bioinductive Collagen Implants Reduce Rotator Cuff Retear. Arthroscopy. 2024. PMID 38331362 ↗Reference — Systematic Review
Acta Orthopaedica Belgica (2024) systematic review (17 studies, 1,062 cases): retear rate 0–18% in Regeneten groups, with significant improvement in pain and function scores. No implant-related complications reported.
Systematic review of bioinductive collagen implant (Regeneten) for rotator cuff tears. Acta Orthop Belg. 2024. PMID 39869884 ↗Reference — Meta-Analysis
Journal of Shoulder and Elbow Surgery (2024) meta-analysis: full-thickness retear rate 8.3%, partial retear rate 1.1%with Regeneten augmentation — improved structural integrity vs repair alone.
Meta-analysis: bioinductive collagen implant augmentation for rotator cuff repair. J Shoulder Elbow Surg. 2024. PMID 38942225 ↗Reference — Systematic Review
KSSTA (2025) systematic review (25 studies): 75–81.7% of patients achieved MCID (minimum clinically important difference) for both pain and function after Regeneten, confirming consistent clinical efficacy.
Systematic review: clinical outcomes of bioinductive collagen implant for rotator cuff. KSSTA. 2025. PMID 39234682 ↗Best Results When Combined
Regeneten is highly effective alone, but combining it with plication suture produces the strongest outcomes.
Plication Suture + Collagen Patch (Regeneten)
The plication suture anchors the articular-side of the torn tendon to bone from below, while the collagen patch reinforces the bursal surface from above. Together, they address both faces of the tear simultaneously — providing comprehensive structural and biological restoration.
About Plication Suture →Book Your Regeneten Surgery Consultation
No general anesthesia · FDA & CE approved material · 12-week free sports rehab